Database Software
Databases PDF Print E-mail
Database name Keywords Description Web ressources Publications
Actin, cytoskeleton, database Actinome is a collection of sequences related to the cytoskeleton. website PMID: 17727702

Alvinella

Alvinella pompejana, Polychaete Annelid, thermostable Alvinella pompejana, the "Pompeii worm", is a Polychaete Annelid (see taxonomy) discovered in 1980. This tubiculous worm colonizes hydrothermal vents where it is faced with extreme and variable physico-chemical conditions including very high temperatures (from 20 to over 80°C), anoxic conditions, low ph, high concentration of heavy metals and sulphids... This environment makes A. pompejana an ideal model for studies aimed at deciphering adaptation in general as well as a unique source of thermostable proteins of eukaryotic origin. website PMID: 20663123
BAliBASE III
version 3
multiple sequence alignment, benchmark, reference alignment A collection of high quality multiple sequence alignments for objective, comparative studies of alignment algorithms. The alignments are constructed based on 3D structure superposition and manually refined to ensure alignment of important functional residues. A number of subsets are defined covering many of the most important problems encountered when aligning real sets of proteins. website PMID: 16044462
PMID: 11125126
PMID: 10068696

GeCo

Genomic context, biostatistics, boxplot radar, average gene mapping deep-sequencing The Genomic Context Database (aka GeCoDB) website is dedicated to DNA-oriented bioinformatics and is more especially focusing on genomic and genic context, whether this context is intrinsec or epigenomic. website Ongoing

GxDb

Gene expression, Transcriptomic database The aim of GxDb is to collect, analyse, manage, query and display Transcriptomics Data. If you have cel files, create a new experiment with its corresponding organism, individual, samples, realexps, etc. Upload your files, run the automatic analysis ... (please, first of all, contact Laëtitia or Raymond) Then query and visualise the results. website Ongoing

GenoretDatabase

EVI-GENORET, Retina, Genoret Database The aim of the Genoret Database is to centralise phenotypic, genomic and proteomic data concerning retinal diseases as well as data concerning patients. This should allow implementation of standards and permit the establishment of common information networking systems. The Genoret Database is a Relational Database whose advantage is to store heterogeneous data in a standard format. It provides an easy manual or automatic access, allowing direct deposits focused on workpackages and workpackage deliverables. website EVI-GENORET Integrated Project
LSHG-CT-2005-512036

ICDS

Interrupted Coding Sequence, ORF Unrecognized frameshifts, in-frame stop codons and sequencing errors lead to Interrupted CoDing Sequence (ICDS) that can seriously affect all subsequent steps of functional characterization, from in silico analysis to high-throughput proteomic projects. Here, we describe the Interrupted CoDing Sequence database containing ICDS detected by a similarity-based approach in 80 complete prokaryotic genomes. website PMID: 16381882

SM2PH-db

Structural Mutation, Phenotype, Disease SM2PH-db (from Structural Mutation to Pathology Phenotypes in Human - database) is a relational database which gathers proteins involved in human monogenic diseases and provides for each of them a combined evolutionary and structural view coupled to mutation and phenotypic data. website PMID: 19921752
PMID: 20543432
PMID: 20164459
 
Programs PDF Print E-mail
Software name Keywords Description Web ressources Publications
AlexSys : Alignment Expert System
Multiple Alignment, Data mining, Machine learning, UIMA, Knowledge based system Although traditional bioinformatics analyses have provided the basis for the extraction of much useful information, today’s data-rich context means that the knowledge discovery process is complicated on the one hand, by the huge amount of heterogeneous data available, and on theother hand, by the next-to-impossible automation of the human expertise required. We developed a new knowledge-based expert system, AlexSys, for complex bioinformatics analyses and its subsequent application to a crucial task: Multiple Sequence Alignment. website PMID:18971242
PMID: 20530533
ARP, Actin related proteins, prediction ARPAnno (Actin Related Proteins Annotation server) is a web tool that automatically annotates protein sequences according to the ARP classification. website PMID: 16195354
BBS, MSA, alignment, Bardet Biedl Syndrome Bardet-Biedl Syndrome Bioinformatics resource. website PMID: 20177705
PMID: 16823392
PMID: 17160889
PMID: 16582908
Oligonucleotide design, probe design, microarray, DNA chips CADO4MI (Computer Assisted Design of Oligonucleotide 4 MIcroarray) is a program for automatic design of oligonucleotides, fully customizable and accessible through a graphical user interface. For an input set of sequences, it allows parameter optimization and can combine multiple designs in distinct sequence databases. website PMID: 17727702

Gscope Gscope

Genomics, integrative software plateform Gscope is an integrated platform allowing the analysis of all kind of genomic data. It is written in Tcl/Tk and runs on all plateforms. It is specially designed to perform high throughput analysis. Gscope is mainly composed of tools necessary to create the basic data, analysis tools, visualisation interfaces. It allows also the creation and feeding of SQL relational databases and the quering and display of the available information through a web based interface (Wscope). Gscope server
Protein family analysis, multiple sequence alignment, sequence annotation MACSIMS (Multiple Alignment of Complete Sequences Information Management System) is a multiple alignment-based information management system that combines the advantages of both knowledge-based and ab initio sequence analysis methods. Structural and functional information is mined automatically from the public databases. In the MACS, homologous regions are identified and the mined data is evaluated and propagated from known to unknown sequences with these reliable regions. MACSIMS provides a unique environment that facilitates knowledge extraction and the presentation of the most pertinent information to the biologist. website PMID: 16792820
Orthology, Inparalogy, Vizualisation OrthoInspector is a software system incorporating an original algorithm for the rapid detection of orthology and inparalogy relations between different species. IIn addition, several visualization tools have been developed to facilitate in-depth studies based on these predictions. It is made available as an independent software suite that can be downloaded and installed for local use. Command line querying facilitates the integration of the software in high throughput processing pipelines and a graphical interface provides easy, intuitive access to results for the non-expert. website

PMID: 21219603

Protein family analysis, multiple sequence alignment, database search PipeAlign is an on-line protein family analysis tool providing both interactive and automatic workbench for the validation, integration and presentation of the biological insights resulting from the analysis. It integrates a 5 step process ranging from the search for sequence homologues in protein sequence and 3D structure databases to the definition of the hierarchical relationship between and within subfamilies. Each step relies upon the results from the previous ones until a validated multiple alignment integrating subfamilies information is produced. The Pipe can also be started from any point and intermediate results are easily consulted. website PMID: 12824430

RReportGenerator

automatic report, statitical analysis, R, Bioconductor, microarray, TCA The aim of RReportGenerator consists in providing a simple and user-friendly graphical user interface (GUI) allowing to run routine statistical analysis using R via predefined analysis scenarios in a local and independent manner. Of course, the large variety of additional libraries on CRAN and Bioconductor may be used with the analysis scenarios. The results (text, figures and tables) are automatically assembled into a report in pdf- (or dvi) format. This may be accompanied by an additional file(s) for exporting (specific) results to other applications (spread-sheet programs, web-browser etc). website
sourceforge
PMID: 18037684
 
Other PDF Print E-mail
Name Keywords Description Web ressources Publications
ontology, evolutionary analysis CDAO (Comparative Data Analysis Ontology) provides extensive conceptual coverage of commonly used concepts in evolutionary analyses in a single framework. It is developed in collaboration with a group of domain scientists specialising in phylogenetic analysis software, the EvoInfo working group (http://evoinfo.nescent.org) . CDAO is used in a number of projects, including nexML, Nexplorer3, TreeBASE, phyloXML. website
sourceforge
PMID: 19812726