Alvinella pompejana
project
Reference:
Insights into metazoan evolution from Alvinella pompejana cDNAs.
Gagniere N, Jollivet D, Boutet I, Brelivet Y, Busso D, Da Silva C, Gaill
F, Higuet D, Hourdez S, Knoops B, Lallier F, Leize-Wagner E, Mary J, Moras D,
Perrodou E, Rees JF, Segurens B, Shillito B, Tanguy A, Thierry JC, Weissenbach
J, Wincker P, Zal F, Poch O, Lecompte O.
BMC Genomics. 2010
Nov 16;11(1):634.
The Pompeii worm
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Alvinella pompejana, the "Pompeii worm", is a Polychaete
Annelid (see taxonomy) considered as the most thermotolerant animal. This tubiculous worm colonizes hydrothermal vents
where it is faced with extreme and variable physico-chemical conditions
including very high temperatures (from 5 to 105 degrees
Celsius), anoxic
conditions, low ph, high concentration of heavy metals and sulphids... This
environment makes A. pompejana an ideal model for studies aimed at
deciphering adaptation in general as well as a unique source of thermostable
proteins of eukaryotic origin. |
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Alvinella
database
On this web site, we present
a searchable database of Alvinella
pompejana sequences from four full length enriched cDNA libraries (whole
animal, gills, pygidium and ventral tissue). Whole animals and dissected tissues have been
collected during the oceanographic Biospeedo cruise on the Pacific Ridge. Full
length cDNA libraries have been constructed and sequenced at the Genoscope (CNS). The database can be queried by blast or text search of
annotations. Different views are available: nucleic cDNA sequence, EST trace
and six-frame translation, contig schematic representation, Consed-like contig
alignment view, MACSIMS annotated protein alignment with customisable features
display, integrative view of the annotation (text mining definition, EC number,
Gene Ontology, Pfam-A domains).
The
sequences have been submitted to the EST section of the EMBL database under
accession numbers FP489021 to FP539727 and FP539730 to FP565142.
Acknowledgements
This work was supported by
institutional funds from INSERM, CNRS and UDS, by European Commission funding
through the SPINE2-COMPLEXES project LSHG-CT-2006-031220 and by
ANR-05-BLAN-0407 grant. The website is hosted by IGBMC.
Contact: lecompte@igbmc.fr